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事例研究：急性皮膚炎症・乾癬モデル
Performing efficacy studies using psoriasis models Psoriasis arises due to the dysregulation of the interplay between the innate and adaptive immune system together with other compartments such as epithelium, vasculature, and cutaneous nervous system. On the cellular...
新規免疫療法の有効性を評価するための免疫表現型解析
It is well-established that syngeneic mouse models represent a powerful tool to evaluate therapies that target the immune system. The key to understanding your immuno-modulatory compound's efficacy is to work with well-characterised models, with known growth kinetics...
Fmr1ノックアウトマウスにおける聴覚事象関連電位（EEG）の記録
July is Fragile X Syndrome (FXS) Awareness month, a time dedicated to raising awareness about this rare genetic disorder, affecting thousands of individuals worldwide. We are deeply committed to accelerating the availability of targeted therapies to improve the lives...
てんかん性脳症モデルにおける脳波記録
September is STXBP1 disorders awareness month, an initiative aimed at raising awareness of STXBP1-related rare genetic disorders, such as epileptic encephalopathy. Although STXBP1-related disorders are rare; STXBP1 is the 5th most common cause of genetic forms of...
代謝性化合物の有効性試験を強化する認知的読み出し
いわゆる西洋型食生活は、過体重または肥満、2型糖尿病および／または非アルコール性脂肪性肝炎（NASH）の患者に見られる代謝機能障害に大きく寄与している一方で、現在の疫学的証拠は西洋型食生活の摂取増加が...
アルツハイマー病モデルにおけるアミロイドβ誘発性神経炎症
Amyloid and Tau mouse models recapitulate pathological processes found in patients with Alzheimer’s Disease (AD), including protein aggregation, neuroinflammation, neurodegeneration, and cognitive impairments. The key to understanding a therapeutic compound's effect...
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