Immunology CRO Services

Comprehensive evaluation of therapeutic candidates, including immune profiling, safety and efficacy testing, dose optimization, and mechanistic insights with InnoSer’s immunology CRO services

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InnoSerを用いた前臨床免疫学研究

✓ Molecular and Immunology Techniques

✓ スマート病理学的評価

✓ 薬理学の専門知識

✓ Validated Models

✓ オーダーメイドの調査設計

✓ 専任研究コーディネーター

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As a European preclinical immunology contract research organization (CRO), InnoSer provides you with an integrated immunology portfolio spanning from in vitro to in vivo research services. InnoSer works with well-published in vitro and in vivo models relevant for multiple indications ranging from hypersensitivity, inflammatory, to autoimmune diseases. By choosing InnoSer as your partner CRO, you will work alongside our expert study directors who take a collaborative approach for your study, accommodating your study timelines and budget needs.

InnoSer’s immunology expert team possesses relevant experience in working with multiple therapy types ranging from novel delivery methods, vaccines, small molecules, biologics to cell and gene therapy approaches. Complemented by our pharmacology expertise (such as target validation, biomarker identification, and validation, as well as PK/PD profiling), the InnoSer team works with you to confidently demonstrate the safety and efficacy profile of your novel investigational compound.

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Preclinical Immunology Disease Model Catalogue

In Vitro Immuno-assays

Perform initial screening tests using InnoSer’s in vitro immunoassays to select your lead candidate compounds and progress to in vivo studies with confidence

DTHマウスモデル

Evaluate your compound’s immunomodulatory or immunosuppressive potential in the delayed-type hypersensitivity (DTH) mouse model

mRNA/RNA Therapies

Vaccine Testing and mRNA/RNA therapies: LNP delivery, in vitro assays, biodistribution, PKPD, immunogenicity, dose optimization and more

炎症性腸疾患マウスモデル

Test the efficacy of your novel compounds to improve gut health in individuals with IBD through InnoSer’s preclinical expertise and portfolio of IBD mouse models

Diabetes Mouse Model

新規開発中の治療法が血糖コントロールと耐糖能に及ぼす効果を検証する提供： InnoSerの専門技術 1型糖尿病糖尿病 mマウス mモデルs

EAEマウスモデル

Investigate your compound’s efficacy on the inflammation and immune component of Multiple Sclerosis using the EAE mouse model

IL-23誘導乾癬マウスモデル

Perform quick efficacy tests to evaluate your novel psoriasis treatment strategies using the acute IL-23-Induced Psoriasis Mouse model

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Immunology Research with InnoSer

Validated research models

As a preclinical immunology CRO, InnoSer performs efficacy studies in well-established and clinically relevant research models. Standardized study protocols ensure consistency and reproducibility of your results. With flexible and fast study start times you can perform your immunology research at an accelerated pace. InnoSer’s expert team continuously works on validating new research models; if you don’t see your research model of choice on our webpage do not hesitate to contact us.

Complemented with molecular and immunology techniques

Carefully designed studies complemented with the most relevant readouts are required to confidently demonstrate your investigational compound’s efficacy. InnoSer offers a wide range of readouts to perform in vitro assays (immune cell activation, immunotoxicity, T-cell activation), cytokine and immune cell profiling (flow cytometry, MSD, ELISA), and biomarker quantification. Additionally, InnoSer works with in-house veterinary pathologists, providing you with accurate and rapid histopathology assessments.

Powered by complementary pharmacology expertise

InnoSer’s immunology CRO services are complemented with pharmacology studies that can be done before or alongside your efficacy studies. Fee-for-service pharmacology studies offered by InnoSer’s team include ADME/ DMPK studies, PK/PD profiling, biodistribution, and early-stage toxicology (dose-response, maximum tolerated dose [MTD], etc.,) studies.

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セリーヌ・エレンス博士、腫瘍学・免疫学主任研究員

当社の免疫腫瘍学研究責任者セリーヌ・エレンス率いる専門家チームが、適切なツールの選択と最適な試験設計の構築を支援します。当該分野への深い理解に基づき、リード化合物の前臨床試験を厳選することで、貴社の医薬品開発を加速するソリューションを提供します。

ヤニック・ファントン博士、最高科学責任者

イノサーの最高科学責任者として、ヤニックはイノサーにおける全ての顧客調査を担当し、科学的・技術的な調整業務を統括している。

よくあるご質問

What is a preclinical immunology CRO?

A preclinical immunology contract research organization (CRO) provides specialized research services to support the development and approval of novel immunomodulatory therapeutics. As a preclinical European immunology CRO, InnoSer regularly partners with leading biotechnology and pharmaceutical industry innovators to:

Offer expert advice and perform a wide range of drug development studies related to pharmacology, early-stage toxicology, and efficacy for various immunomodulatory compound testing.
Test the therapeutic profile of novel investigational compounds utilizing highly translational in vitro and in vivo models for autoimmune, inflammatory, and hypersensitivity diseases.
Develop and validate novel models (e.g., humanized mouse models for efficacy testing of various immunomodulatory compounds).
Partnering with a preclinical immunology CRO like InnoSer provides you with access to cutting-edge resources, accelerates your drug development process, and allows your team to focus on its core objectives without the need for a complex in-house setup.

Contact InnoSer to discuss how we can support your preclinical immunology research goals.

Why should I choose InnoSer as my partner CRO for preclinical immunology research?

At InnoSer, we provide expertise, flexibility, and tailored solutions to support your preclinical immunology research, helping you generate reliable, high-quality data while keeping you thoroughly informed throughout the process. By working with InnoSer, you can:

Assess the pharmacologic (e.g., PK/PD, tolerability, dose-response) and toxicologic profile (e.g., maximum tolerated dose) of your compound before moving to efficacy studies
Demonstrate the efficacy profile of your novel immunomodulatory compounds with our highly translationally relevant in vitro and in vivo models for a range of autoimmune, inflammatory, and hypersensitivity disorders
Assess immune cell profiling with advanced technologies: obtain valuable insights into modulating cytokine profiles, immune cell recruitment, and immune memory formation using flow cytometry and mesoscale discovery (MSD)
Track the biodistribution of your compounds in real-time: leverage InnoSer’s expertise in IVIS Imaging and monitor your drug distribution in vivo
Get expert guidance and real-time study updates: Stay informed with in-life study reports, mid-study data reviews, and a secure data-sharing platform.

Ready to Accelerate Your Immunology Research? Contact InnoSer today to discuss how our preclinical immunology CRO services can support your therapeutic development and help you achieve your research goals faster.

What immunology models should I choose for my research?

The choice of immunology models depends on the stage of your research, specific disease area, mechanism of action (MoA) of your compound, as well as objectives of your research. For example, if you have multiple lead compounds and you would like to select only a few to progress to efficacy studies, in vitro assays may be a suitable choice due to the lower price and time investment needed.

To support lead optimization, complementary studies such as pharmacokinetics (PK), pharmacodynamics (PD), tolerability, and dose-response assessments can provide critical data before advancing to efficacy testing. These studies help optimize dosing regimens, refine formulations, and prioritize compounds with the most favorable PK/PD profiles.

When moving into in vivo efficacy studies, disease-specific models are essential for assessing your compound’s therapeutic potential. For example, InnoSer’s EAE mouse models are widely used for multiple sclerosis research, while IBD mouse models help evaluate test compounds for Crohn’s disease and ulcerative colitis. Psoriasis models (such as IL-23-induced skin inflammation) allow for the efficacy of compounds on ameliorating skin inflammation, and DTH mouse models are useful for assessing T-cell mediated immune responses.

At InnoSer, our expert team works closely with you to identify the most suitable models and plan an efficient study strategy, ensuring your research progresses smoothly without any costly delays. Contact us today to discuss your research needs!

I don't see my model of choice in your mouse model list, does InnoSer have capabilities to validate new immunology disease models on request?

Yes! At InnoSer, we offer flexible and customizable preclinical immunology CRO solutions, including the development and validation of new immunology research models to meet your specific research needs. If your model of interest is not listed on our website, reach out to our team, who will work together with you to develop and validate novel in vivo and/or in vitro models, ensuring reproducibility and reliability for your preclinical research.

Speak with our immunology experts to discuss your specific study goals.

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Explore and compare our immunology models to identify the perfect model for your study needs.

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好奇心を持ち続けよう：さらに探求できる記事

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AAALAC認定

InnoSerはAAALAC認証を取得し、責任ある動物ケアと利用への取り組みを実証しています。AAALAC Internationalは、自主的な認証および評価プログラムを通じて科学における動物の適切な扱いを推進する非営利組織です。InnoSerのオランダおよびベルギー施設は、それぞれ2016年および2020年よりAAALAC認証を取得しています。AAALAC認証プログラムの詳細はこちらをご覧ください。

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動物福祉

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