CatWalk™ Automated Gait Analysis System
The CatWalk™ XT (Noldus IT, The Netherlands) is a gait analysis system for quantitative assessment of gait and locomotion in mice. It is the most sophisticated system for quantification of a wide range of parameters related to footprints and gait in unforced moving animals.
The CatWalk™ gait analysis system enables quantification of a wide range of parameters related to footprint and gait in animals.
The CatWalk™ gait analysis system enables quantification of a wide range of parameters related to footprint and gait in animals.
Thy1-P301L mice show less aggressive pathophysiological development. At 6 months of age, subtle, but significant changes in gait and footprint size are observed on the Catwalk test indicating fine motor skills deficit. By 10 months or older, these mice show profound motor function deficits.
The CatWalk™ gait analysis system enables quantification of a wide range of parameters related to footprint and gait in animals.
WT mice support themselves with combination of diagonal paws, however this is significantly lower in the C3-PMP22 preclinical mouse model of Charcot Marie Tooth disease type 1A (CMT1A).
The CatWalk™ gait analysis system enables quantification of a wide range of parameters related to footprint and gait in animals.
6-month-old female hemizygous Prp-TDP43-Q331K (JAX #017933) tested in the CatWalk™ Gait Analysis show abnormal walking patterns (Stride length). Stride length (cm) refers to the distance between successive placements of the same paw.
The CatWalk™ gait analysis system enables quantification of a wide range of parameters related to footprint and gait in animals.
6-month-old female hemizygous Prp-TDP43-Q331K (JAX #017933) tested in the CatWalk™ Gait Analysis show abnormal walking patterns (Body speed). Body speed (cm/s) refers to the body movement speed between two consecutive steps of the same paw.
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