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MDX Mouse Model Validation Data

MDX Mouse Model Validation Data

This month we’re highlighting one of the most commonly used mouse models to study Duchenne Muscular Dystrophy (DMD) – the MDX mouse model B10.mdx), and explore how our advanced services can support your efficacy studies in DMD.   The X-linked muscular dystrophy (MDX)...

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Pancreatic Cancer PDX Models

Pancreatic Cancer PDX Models

Last month, November, represented Pancreatic Cancer Awareness Month; a time to focus on the challenges posed by one of the most aggressive and lethal cancer types. Pancreatic cancer accounts for approximately 3% of all diagnosed cancers in Europe, with pancreatic...

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Therapeutic targets for ADPKD

Therapeutic targets for ADPKD

In ADPKD, mutations in the PKD1 or PKD2 gene cause changes in polycystin 1 or 2 (PC1 and PC2) expression, which in turn interferes with several intracellular signaling pathways that are e.g., involved in cell proliferation, fluid secretion, and ciliary function. The...

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RENCA Mouse Mouse Model of Renal Cancer

RENCA Mouse Mouse Model of Renal Cancer

Approximately 400,000 people are diagnosed with kidney cancer annually. Kidney tumors are classified into different subtypes based on the cell of origin. Over 85% of malignant renal cell tumors are RCC, with the other 15% being nephroblastic, mesenchymal and...

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