InnoSer News
The Application of Bioluminescence Imaging in Preclinical Oncology Research and Beyond
Introduction into the power of bioluminescence imaging Bioluminescence imaging (further referred to as BLI in this article) is an in vivo imaging technique that allows non-invasive longitudinal monitoring of in vivo processes, commonly applied in preclinical oncology...
Latest cardiovascular and metabolic research news
InnoSer offers a selection of gold standard cardio-metabolic disease models in rodents, supporting custom studies to optimize the preclinical development of your drug candidates. Learn more about you can leverage InnoSer’s experience and expertise in the...
PK/PD and Tolerability Testing in the ADPKD Mouse Model
The lead optimisation phase is a crucial process during which you investigate and select the most promising preclinical candidate(s) to progress to efficacy testing using animal models of human diseases. Pharmacokinetic (PK) and Pharmacodynamic (PD) profiling helps...
In vivo Tumorigenicity Testing to Evaluate Your Therapeutics’ Safety
For all novel therapy types in the immuno-oncology field such as immunotherapies, small molecule, biologics, ATMPs, gene therapeutics etc., rigorous preclinical research is the key to success in clinical trials. Learn more about how InnoSer’s expertise in the...
How to obtain the most value out of your neurodegenerative disease research models?
To date, large ongoing efforts are being made to provide well-characterised animal models which are suitable for investigating novel therapeutics. To ensure full confidence in the efficacy profile of novel therapeutic agents, efficacy testing often needs to be...
InnoSer to Present Novel Data at AD/PD 2024 Showcasing in Vitro Neurodegenerative Disease Modelling Capabilities
We are thrilled to announce that InnoSer, as an innovative preclinical contract research organization (CRO), will be actively participating in the upcoming AD/PD 2024 Conference taking place in Lisbon, Portugal on March 5-9, 2024. The theme of AD/PD 2024 is striving...
Getting the Most out of Bioluminescent Imaging for Your Research
The application of bioluminescence imaging (BLI) in preclinical research studies offers quantitative, sensitive, longitudinal real-time data and can be applied in: Validation of cancer cell lines, helping to establish improved preclinical cancer mouse models. ...
The Application of Cystic Index in the ADPKD Mouse Model
The kidneys of autosomal dominant polycystic kidney disease (ADPKD) patients progressively enlarge due to the formation and expansion of fluid-filled cysts. However, currently there is no available therapy for ADPKD patients that targets the growth of cysts,...
The Importance of Including Translational Kidney Function Readouts in Your Preclinical Research: Transdermal GFR Measurement
Preclinical Nephrology Research Preclinical studies aiming to assess kidney function in animal models of kidney disease or in response to a test compound have traditionally included readouts such as serum creatinine and blood urea nitrogen (BUN). However, the use of...