Immunology CRO services
Comprehensive evaluation of therapeutic candidates, including immune profiling, safety and efficacy testing, dose optimization, and mechanistic insights with InnoSer’s immunology CRO services.
As a European preclinical immunology contract research organization (CRO), InnoSer provides you with an integrated immunology portfolio spanning from in vitro to in vivo research services. InnoSer works with well-published in vitro and in vivo models relevant for multiple indications ranging from hypersensitivity, inflammatory, to autoimmune diseases. By choosing InnoSer as your partner CRO, you will work alongside our expert study directors who take a collaborative approach for your study, accommodating your study timelines and budget needs.
InnoSer’s immunology expert team possesses relevant experience in working with multiple therapy types ranging from novel delivery methods, vaccines, small molecules, biologics to cell and gene therapy approaches. Complemented by our pharmacology expertise (such as target validation, biomarker identification, and validation, as well as PK/PD profiling), the InnoSer team works with you to confidently demonstrate the safety and efficacy profile of your novel investigational compound.
Immunology Model Options
In Vitro Immunoassays
Perform initial screening tests using InnoSer’s in vitro immunoassays to select your lead candidate compounds and progress to in vivo studies with confidence.
IL-23 Induced Psoriasis Mouse Model
Perform quick efficacy tests to evaluate your novel psoriasis treatment strategies using the acute IL-23-Induced Psoriasis Mouse model.
mRNA/RNA Therapies
Vaccine Testing and mRNA/RNA therapies: LNP delivery, in vitro assays, biodistribution, PKPD, immunogenicity, dose optimization and more
DTH Mouse Model
Evaluate your compound’s immunomodulatory or immunosuppressive potential in the delayed-type hypersensitivity (DTH) mouse model.
Diabetes Mouse Model
Test your novel investigational therapy’s effect on glycemic control and glucose tolerance thanks to InnoSer’s expertise in Type 1 diabetes mouse models.
Immunology research with InnoSer
Validated research models
As a preclinical immunology CRO, InnoSer performs efficacy studies in well-established and clinically relevant research models. Standardized study protocols ensure consistency and reproducibility of your results. With flexible and fast study start times you can perform your immunology research at an accelerated pace. InnoSer’s expert team continuously works on validating new research models; if you don’t see your research model of choice on our webpage do not hesitate to contact us.
Complemented with molecular and immunology techniques
Carefully designed studies complemented with the most relevant readouts are required to confidently demonstrate your investigational compound’s efficacy. InnoSer offers a wide range of readouts to perform in vitro assays (immune cell activation, immunotoxicity, T-cell activation), cytokine and immune cell profiling (flow cytometry, MSD, ELISA), and biomarker quantification. Additionally, InnoSer works with in-house veterinary pathologists, providing you with accurate and rapid histopathology assessments.
Powered by complementary pharmacology expertise
InnoSer’s immunology CRO services are complemented with pharmacology studies that can be done before or alongside your efficacy studies. Fee-for-service pharmacology studies offered by InnoSer’s team include ADME/ DMPK studies, PK/PD profiling, biodistribution, and early-stage toxicology (dose-response, maximum tolerated dose [MTD], etc.,) studies.
The people behind your research
Céline Erens, PhD, Immunology Study Director
An expert team led by our immunology study director; Céline Erens works together with you to help you set up optimal study designs. Curating the preclinical testing of your lead compounds with a deep understanding of the field is your solution to accelerating your drug development.
AAALAC Accreditation
InnoSer has earned the AAALAC accreditation, demonstrating our commitment to responsible animal care and use. AAALAC International is a nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. Our accreditation is valid for three years, incl. 2023. Read more about the AAALAC accreditation programme here.
Animal Welfare
The 3Rs impact everything from policy and regulatory change to the development and uptake of new technologies and approaches. This is why Innoser has ongoing commitment and monitoring of these processes. The steps we practice maximize our ability to replace, reduce and refine animal involvement and facilitate our commitment to these principles when it comes to research and drug development.
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