Immuno-Oncology in vitro Assays
Perform initial screening tests using InnoSer’s in vitro immuno-oncology assays to select your lead candidate compounds and progress to in vivo studies with confidence
InnoSer’s Immuno-Oncology In Vitro Assay Services
Immuno-oncology in vitro assays are carried out using cancer-associated rodent (murine, rat) or human immortalized cell lines, representing a powerful tool to perform high throughput drug screening studies. Accordingly, InnoSer offers a selection of commercially available cancer cell lines ideal for progressing your compound from a hit to a lead candidate.
Assays using rodent or human cell lines are efficient, relatively inexpensive, and easy to set up. Therefore, providing you with a wealth of information on your compound efficacy, and mechanisms of action. However, to capture patient and tumor heterogeneity early on in your initial in vitro screening studies, InnoSer recommends working with patient-derived organoids (tumoroids). Accordingly, in vitro assays can be used before or in conjunction with running your in vivo studies in InnoSer’s syngeneic mouse models or cell line-derived xenograft (CDX) mouse models.
✓ Cancer-associated tumor and microenvironment-associated cell lines (human and rodent).
✓ Co-cultures (human and rodent) and 3D cell cultures (tumoroids).
Developing new, safe, and efficacious anticancer therapies is an extremely intricate process. As a preclinical oncology contract research organization (CRO), InnoSer partners with you to help you navigate the complexities of this research area.
Scientists at InnoSer collaborate with you to develop the most optimal study design to help answer your research questions in the most cost-effective way. With flexible and fast study start times you can perform your research at an accelerated pace. By outsourcing your preclinical oncology studies to InnoSer, you gain access to our in vitro and in vivo oncology drug development portfolio.
Unlock the Right Tools for Your Research.
Explore and compare our oncology platforms to identify the perfect model for your study needs.
Immuno-oncology in vitro assays Sample Data
The PD-1 PD-L1 blockade assay offered by InnoSer is an in vitro based assay that enables you to assess your PD-1 PD-L1 therapeutics’ MoA.
Representative dose-response curve for reference antibody expressed as fold induction.
Key immuno-oncology in vitro assays
The People Behind Your Research
Céline Erens, PhD, Immunology Study Director
An expert team led by our immuno-oncology study director, Céline Erens helps you choose the right tools and set up optimal study designs. Curating the preclinical testing of your lead compounds with a deep understanding of the field is your solution to accelerating your drug development.
Yanick Fanton, PhD, Chief Scientific Officer
As Chief Science Officer at InnoSer, Yanick is responsible for all customer studies at InnoSer and takes care of the scientific and technical coordination.
Oncology Board Members
Prof. Dr. Esther Wolfs
A member of InnoSer’s Scientific Advisory Board, Dr. Wolfs is a leading researcher in stem cell therapy. Currently a professor at the University of Hasselt, Ester uses stem cells in anticancer therapy and as a model to study Charcot-Marie-Tooth disease type 1A.
MD, PhD Marije Slingerland
A member of InnoSer’s Scientific Advisory Board, Dr. Slingerland from Leiden University Medical Center focuses on clinical trials in gastrointestinal cancer and in head and neck cancer, particularly on intratumoral immune parameters.
Discover Other Related Oncology Research Models
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Exploring InnoSer’s Key In vitro Oncology Services: PD-1 PD-L1 Blockade Assay
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RENCA Mouse Mouse Model of Renal Cancer
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Tumor microenvironment (TME) multiplex immunophenotyping analyses
The use of preclinical orthotopic tumors to better recapitulate the tumor microenvironment (TME) Complex interactions between the cellular and structural components of the tumor microenvironment (TME) composed of tumor cells, fibroblasts, endothelial cells, immune...
AAALAC Accreditation
InnoSer has earned the AAALAC accreditation, demonstrating our commitment to responsible animal care and use. AAALAC International is a nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. Our accreditation is valid for three years, incl. 2023. Read more about the AAALAC accreditation programme here.
Animal Welfare
The 3Rs impact everything from policy and regulatory change to the development and uptake of new technologies and approaches. This is why InnoSer has ongoing commitment and monitoring of these processes. The steps we practice maximize our ability to replace, reduce and refine animal involvement and facilitate our commitment to these principles when it comes to research and drug development.
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