Grip Strength Test
During the Grip Strength test, the neuromuscular function of a mouse is assessed by measuring the peak force a mouse applies by grasping a bar connected to force meter. Five trials with front paws are followed by five trials with both the front and hind paws combined. The median of these five trials is used as a measure of grip strength.
Grip Strength test assesses the neuromuscular function of a mouse by measuring the peak force a mouse applies by grasping a bar connected to force meter.
High expression of mutated (P301S) toxic tau proteins in the brainstem and spinal cord leads to a progressive decrease in grip strength from 14 weeks of age onwards.