Balance Beam
The Balance Beam test is a sensitive, straightforward behavioral assay used to evaluate motor coordination, balance, and sensorimotor function in rodents
The Balance Beam sensorimotor coordination test scores the ability of mice to traverse a stationary horizontal rod. In this test, a rodent is placed on one end of a narrow beam and encouraged to cross to a safe platform at the other end. As the rodent moves, you can measure its ability to maintain balance, as well as record errors such as paw slips or falls. The time taken to cross the beam, the number of slips, and whether the rodent falls off the beam are key parameters for assessing motor coordination and balance.
This test is a highly effective way to measure gross motor control and sensorimotor integration in rodents. If your research involves candidate compounds that can ameliorate the impaired motor coordination skills in multiple neurological diseases such as Parkinson’s disease, stroke, or multiple sclerosis, this test can provide quantitative preclinical data on motor deficits. It is especially sensitive to mild impairments, making it a valuable tool for tracking the progression of motor symptoms or the impact of therapeutic interventions. As part of InnoSer’s innovative preclinical neurology CRO solutions, this sensorimotor function test is commonly used in combination with several other motor tests, such as Grip Strength test, Rotatod, or CatWalk automated gait analysis system. However, as each motor function test is unique, targeting different motor function skills in rodents, we recommend you discuss the most appropriate motor function behavioral test battery with our neurology study directors.
Example data featuring the Balance Beam sensorimotor test:
The Balance Beam sensorimotor coordination test scores the ability of mice to traverse a stationary horizontal rod.
Vanishing white matter mice show impairments in the Balance Beam test.
The Balance Beam sensorimotor coordination test scores the ability of mice to traverse a stationary horizontal rod.
C3-PMP22 mice have reduced motor function, as indicated by a higher number of slips.