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アルツハイマー病およびパーキンソン病に対する薬剤の有効性をスクリーニングするためのトランスレーショナルなin vitroアッセイ
Modelling neurodegenerative disease using in vitro assays Neurodegenerative drug development is held back due to the lack of appropriate models that help accelerate the pace at which novel therapeutic candidates move through the drug development pipeline. As such, in...
野生型またはヒト化マウスにおける検証済み遅延型過敏反応アッセイ
Delayed-type hypersensitivity (DTH) in vivo assay represents a relatively quick and useful approach for evaluating the efficacy of potential immunomodulatory or immunosuppressive compounds. By challenging the cell-mediated immune response, you obtain valuable...
腎疾患モデルにおける経皮的GFR測定の妥当性検証
At InnoSer, we offer several readouts to assess the disease progression and the efficacy of novel targeted polycystic kidney disease (PKD) compounds. However, we understand that it remains a significant challenge to access crucial readouts that are recognized by...
事例研究：急性皮膚炎症・乾癬モデル
Performing efficacy studies using psoriasis models Psoriasis arises due to the dysregulation of the interplay between the innate and adaptive immune system together with other compartments such as epithelium, vasculature, and cutaneous nervous system. On the cellular...
新規免疫療法の有効性を評価するための免疫表現型解析
It is well-established that syngeneic mouse models represent a powerful tool to evaluate therapies that target the immune system. The key to understanding your immuno-modulatory compound's efficacy is to work with well-characterised models, with known growth kinetics...
Fmr1ノックアウトマウスにおける聴覚事象関連電位（EEG）の記録
July is Fragile X Syndrome (FXS) Awareness month, a time dedicated to raising awareness about this rare genetic disorder, affecting thousands of individuals worldwide. We are deeply committed to accelerating the availability of targeted therapies to improve the lives...
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