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Wie lässt sich der größtmögliche Nutzen aus Ihren Forschungsmodellen für neurodegenerative Erkrankungen ziehen?
To date, large ongoing efforts are being made to provide well-characterised animal models which are suitable for investigating novel therapeutics. To ensure full confidence in the efficacy profile of novel therapeutic agents, efficacy testing often needs to be...
InnoSer präsentiert auf der AD/PD 2024 neue Daten, die die Möglichkeiten der In-vitro-Modellierung neurodegenerativer Erkrankungen verdeutlichen
We are thrilled to announce that InnoSer, as an innovative preclinical contract research organization (CRO), will be actively participating in the upcoming AD/PD 2024 Conference taking place in Lisbon, Portugal on March 5-9, 2024. The theme of AD/PD 2024 is striving...
So nutzen Sie die Vorteile der Biolumineszenz-Bildgebung optimal für Ihre Forschung
The application of bioluminescence imaging (BLI) in preclinical research studies offers quantitative, sensitive, longitudinal real-time data and can be applied in: Validation of cancer cell lines, helping to establish improved preclinical cancer mouse models. ...
Die Anwendung des Zystenindexes im ADPKD-Mausmodell
The kidneys of autosomal dominant polycystic kidney disease (ADPKD) patients progressively enlarge due to the formation and expansion of fluid-filled cysts. However, currently there is no available therapy for ADPKD patients that targets the growth of cysts,...
Die Bedeutung der Einbeziehung translationaler Nierenfunktionsparameter in Ihre präklinische Forschung: Transdermale GFR-Messung
Preclinical Nephrology Research Preclinical studies aiming to assess kidney function in animal models of kidney disease or in response to a test compound have traditionally included readouts such as serum creatinine and blood urea nitrogen (BUN). However, the use of...
eIF2B-Modulatoren bei schwindender weißer Substanz
Vanishing White Matter (VWM) disease is a rare and fatal leukodystrophy, caused by recessive mutations in the five genes encoding the protein complex eukaryotic translation initiation factor 2B (eIF2B). eIF2B plays a crucial role in initiating and regulating the...
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