Cognitive Tests – T-Maze Spontaneous Alternation
The T-Maze Spontaneous Alternation Test is a widely used behavioral assay that assesses working memory, cognitive flexibility, and decision-making in rodents
Key Research Model Applications of T-Maze Spontaneous Alternation
Short-term spatial memory can be assessed in a T-maze. During a sample trial, the mouse is placed in the base of the “T” to explore the maze. After an entry into one other arm, it is contained in this arm for 30 seconds by lowering a guillotine door at the entrance of the arm. During the test trial, the mouse is placed back into the start arm. During the test trial, the mouse is placed back into the starting arm. A successful alternation is scored if the mouse chooses to enter the previously non-visited arm, indicating the acquisition of spatial memory of previously visited arm.
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T-Maze Spontaneous Alternation Sample Data
Short-term spatial memory can be assessed in a T-maze. A successful alternation is scored if the mouse chooses to enter the previously non-visited arm, indicating that it remembered which arm it visited before.
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