Both male and female mice will build a nest when they are provided with suitable building material. The nestbuilding requires a complex set of behaviours that are typically impacted by neurological diseases and/or pharmacological interventions that are affecting hippocampal function. To assess nest building behaviour, mice are provided with additional nesting material. The next morning, nest quality is scored on a scale from 1-5.

Most commonly used in combination with:

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Preclinical behavioral test for drug development

Related neurology resources

Neurology Platform Overview

Highly relevant neurology models to facilitate preclinical drug development

Parkinson's Disease

InnoSer offers unique behavioral services using in vivo models such as MPTP, 6-OHDA induced models, but also genetic (GBA, LRKK2) and alpha-synuclein (both transgenic and seeding).

Alzheimer's Disease

Complimentary range of models and unique behavioural services that recapitulate key characteristics of Alzheimer’s Disease in vivo.