Motor Function Tests – Wire Hanging Test
The wire hanging test is a widely utilized behavioral assay for assessing muscle strength, endurance, and motor coordination in rodents
Key Research Model Applications of Wire Hanging Test
In the wire hanging test, rodents are placed on a horizontal wire or grid, where they instinctively grasp the surface with their forelimbs and hindlimbs to prevent falling. After the mouse has grasped the wire with its front paws, the time it takes for the mouse is recorded to determine whether neuromuscular or motor impairments are present.
The wire hanging test evaluates their ability to sustain grip and maintain posture over time, offering an indication of muscle strength, coordination, and endurance. This test is sensitive to neuromuscular impairments and is often used to track recovery or the efficacy of therapeutic interventions. Contact us to learn more about how we can help advance your studies with precise, reproducible results and comprehensive data analysis.
✓ Neuromuscular dysfunction models.
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Wire Hanging Test
The wire test is started by hanging with two forepaws on the wire, and depending on the functional ability of the mouse it can also use the hind limbs and tail.
The People Behind Your Research
Thomas Vogels, PhD, In Vivo Neurology Study Director
Leads an expert team of scientists with vast experience in our Neurology models to help you choose the right model and guide your optimal study design. We provide the solution to accelerating your drug development.
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AAALAC Accreditation
InnoSer has earned the AAALAC accreditation, demonstrating our commitment to responsible animal care and use. AAALAC International is a nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. Our accreditation is valid for three years, incl. 2023. Read more about the AAALAC accreditation programme here.
Animal Welfare
The 3Rs impact everything from policy and regulatory change to the development and uptake of new technologies and approaches. This is why InnoSer has ongoing commitment and monitoring of these processes. The steps we practice maximize our ability to replace, reduce and refine animal involvement and facilitate our commitment to these principles when it comes to research and drug development.
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