Patient-derived Organoids (Tumoroids)
Perform initial screening tests using InnoSer’s in vitro immuno-oncology assays to select your lead candidate compounds and progress to in vivo studies with confidence
InnoSer’s Patient-derived Organoids (tumoroids) Model Services
Patient-derived organoids (tumoroids) represent a complex 3D in vitro organoid (tumoroid) culture system established from resected tumor samples obtained from oncologic patients. Preserving the tumor and patient heterogeneity, patient-derived organoids (tumoroids) represent a powerful tool to screen multiple lead compounds to understand patient-specific drug responses.
Therefore, high-throughput in vitro assays carried out using patient-derived organoids (tumoroids) are highly relevant for a variety of therapies. Compared to immuno-oncology in vitro assays using cancer-associated rodent or human cell lines, patient-derived organoids (tumoroids) better represent patient heterogeneity.
Accordingly, in combination with InnoSer’s patient-derived xenograft (PDX) models, that can be studied in immunodeficient or humanized mouse models, this approach provides you with seamless access from in vitro to in vivo testing using the same parental tumor samples.
✓ Wide range of cancer types available.
✓ High-throughput drug screening capabilities.
✓ Well-characterized parental tumor samples (RNA seq, hot spot mutations, histopathology).
✓ Access to snap frozen and PFA preserved samples for additional testing.
Developing new, safe, and efficacious anticancer therapies is an extremely intricate process. As a preclinical oncology contract research organization (CRO), InnoSer partners with you to help you navigate the complexities of this research area.
Scientists at InnoSer collaborate with you to develop the most optimal study design to help answer your research questions in the most cost-effective way. With flexible and fast study start times you can perform your research at an accelerated pace. By outsourcing your preclinical oncology studies to InnoSer, you gain access to our in vitro and in vivo oncology drug development portfolio.
Unlock the Right Tools for Your Research.
Explore and compare our oncology platforms to identify the perfect model for your study needs.
Key Patient-derived Organoid (Tumoroid) Models Readouts
The People Behind Your Research
Céline Erens, PhD, Immunology Study Director
An expert team led by our immuno-oncology study director, Céline Erens helps you choose the right tools and set up optimal study designs. Curating the preclinical testing of your lead compounds with a deep understanding of the field is your solution to accelerating your drug development.
Yanick Fanton, PhD, Chief Scientific Officer
As Chief Science Officer at InnoSer, Yanick is responsible for all customer studies at InnoSer and takes care of the scientific and technical coordination.
Oncology Board Members
Prof. Dr. Esther Wolfs
A member of InnoSer’s Scientific Advisory Board, Dr. Wolfs is a leading researcher in stem cell therapy. Currently a professor at the University of Hasselt, Ester uses stem cells in anticancer therapy and as a model to study Charcot-Marie-Tooth disease type 1A.
MD, PhD Marije Slingerland
A member of InnoSer’s Scientific Advisory Board, Dr. Slingerland from Leiden University Medical Center focuses on clinical trials in gastrointestinal cancer and in head and neck cancer, particularly on intratumoral immune parameters.
Discover Other Related Oncology Research Models
Stay Curious: More Articles to Explore
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Tumor microenvironment (TME) multiplex immunophenotyping analyses
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AAALAC Accreditation
InnoSer has earned the AAALAC accreditation, demonstrating our commitment to responsible animal care and use. AAALAC International is a nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. Our accreditation is valid for three years, incl. 2023. Read more about the AAALAC accreditation programme here.
Animal Welfare
The 3Rs impact everything from policy and regulatory change to the development and uptake of new technologies and approaches. This is why InnoSer has ongoing commitment and monitoring of these processes. The steps we practice maximize our ability to replace, reduce and refine animal involvement and facilitate our commitment to these principles when it comes to research and drug development.
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