News, Resources, Updates
A scientific hub to keep you informed about our latest research and company updates.
Total kidney volume (TKV) as a translationally relevant, non-invasive disease progression readout
In this month's newsletter, we invite you to explore how InnoSer's longitudinal total kidney volume (TKV) assessment via non-invasive ultrasound imaging in our ADPKD mouse model provides a clinically aligned structural readout that directly supports decision-making in...
![Translational Neuroscience: Comprehensive longitudinal profiling of the Tau[P301S] female vs male mice](https://www.innoserlaboratories.com/wp-content/uploads/2026/06/Female-TauP301S-mice-show-early-spontaneous-hyperactivity-in-automated-home-cages-PhenoTyperTM-229375_400x250.png)
Translational Neuroscience: Comprehensive longitudinal profiling of the Tau[P301S] female vs male mice
In this month’s newsletter, we highlight and build upon our knowledge working with the Tau[P301S] mouse model (originally described by Allen et al., 2002), and its applicability in preclinical research.Female and male...
Clinically relevant biomarker panels for comprehensive efficacy studies in Alzheimer’s Disease mouse models
InnoSer's validated Alzheimer's disease (AD) mouse models are equipped with translationally relevant biomarker readout panels — spanning amyloid-beta (Aβ) species, phosphorylated Tau isoforms, and the early, sensitive hallmark of neurodegeneration, neurofilament light...
Knocking out Pkd1 in the P40 mouse model enables extended dosing windows and long-term efficacy studies
It is well-established that ADPKD shows heterogeneous disease onset and progression in patients, necessitating preclinical models that capture the heterogeneous disease penetration observed in patients. Therefore, new datasets in our adult-onset (also referred to as...
![Proven Compound Susceptible Tau[P301S] Mouse Model for Preclinical Proof of Concept](https://www.innoserlaboratories.com/wp-content/uploads/2026/03/Proven-Compound-susceptible-TauP301S-mouse-model-for-preclinical-proof-of-concept--400x250.png)
Proven Compound Susceptible Tau[P301S] Mouse Model for Preclinical Proof of Concept
The Tau[P301S] mouse remains one of the most established in vivo models for evaluating therapeutics targeting tauopathies including Alzheimer's disease and frontotemporal dementia (FTD). Presented at AD/PD 2025 in Vienna, this poster provides comprehensive...
InnoSer Presents New Data at the 8th CKD Summit 2026: Advancing Preclinical Models for ADPKD Research
Next week, the kidney research community will gather in Boston for the 8th CKD Summit 2026, a premier event that brings together clinicians, researchers, and industry experts to discuss the latest advances in chronic kidney disease (CKD) research and therapy...
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