Amyotrophic Lateral Sclerosis – ALS Mouse Models
Explore our advanced preclinical ALS mouse models, crucial for preclinical efficacy studies and understanding disease mechanisms
Your Preclinical Amyotrophic Lateral Sclerosis Research with InnoSer
✓ Behavioral & Cognitive Tests
✓ Smart Pathological Assessments
✓ Fast Study Initiation
✓ Tailored Study Designs
✓ Dedicated Research Co-oridnators
As a European preclinical neurology contract research organization (CRO), InnoSer provides you with a portfolio of Amyothropic Lateral Sclerosis (ALS) mouse models relevant for performing preclinical efficacy research studies. By choosing InnoSer as your partner CRO, you will work alongside our expert study directors who take a collaborative approach for your study, accommodating your study timelines and budget needs. InnoSer’s neurology expert team possesses relevant experience in working with multiple therapy types ranging from small molecules, peptides, enzymes, oligonucleotides, gene therapy (viral vectors – e.g.. AAVs) and immunotherapies (antibody/vaccine immunotherapies).
InnoSer offers multiple ALS mouse models relevant for preclinical research, including the SOD1-G93A transgenic ALS mouse model, TDP-43 transgenic mouse models and TDP-43 seeding models using recombinant or patient-derived seeds. However, as each model is unique, modelling distinct pathophysiological aspects of ALS, we recommend you discuss the most appropriate model with our neurology study directors.
InnoSer’s Available ALS Mouse Models
In Vitro Neurology Assays
Screen your lead candidate compounds using InnoSer’s in vitro neurology assays to progress to preclinical in vivo studies with confidence
SOD1-G93A Transgenic ALS Mouse Model
InnoSer offers unique behavioral research services with the SOD1-G93A transgenic mouse model.
TDP-43 Transgenic Mouse Model
InnoSer offers services with several different transgenic TDP-43 mouse models that replicate the TDP-43 proteinopathy in ALS and FTD patients.
TDP-43 Seeding Mouse Models
InnoSer offers extensive preclinical research expertise with TDP-43 seeds using patient-derived brain extracts.
Don’t See Your Model? We Can Help!
Our experts specialize in tailored solutions to meet your unique research needs. Let’s discuss how we can support your project.
The People Behind Your Research
Jolien Beekens, PhD, In Vitro Neurology Study Director
With in vitro screening methods available as a suited first step in your development process our team of experts have the experience to optimise your study design process.
Thomas Vogels, PhD, In Vivo Neurology Study Director
Leads an expert team of scientists with vast experience in our Neurology models to help you choose the right model and guide your optimal study design. We provide the solution to accelerating your drug development.
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