Neurology CRO Services
Take advantage of InnoSer’s neurology CRO services spanning in vitro to in vivo research models and expertise
Preclinical Neuro-science Research with InnoSer
✓ Behavioral & Cognitive Tests
✓ Smart Pathological Assessments
✓ Fast Study Initiation
✓ Tailored Study Designs
✓ Dedicated Research Co-oridnators
InnoSer offers an integrated neurology CRO services portfolio spanning from in vitro to in vivo research services. Our experts facilitate a collaborative approach ensuring we accelerate your drug development process using in-depth knowledge of the models in our portfolio to provide reliable experimental data. We offer a selection of in vitro, ex vivo,, and in vivo models for testing new and innovative compounds within the challenging research area of neurodegenerative diseases. In addition, our team has significant expertise in neuromuscular, rare genetic diseases, neurodevelopmental and psychiatric disorder studies.
InnoSer’s neurology expert team possesses relevant experience in working with multiple oncology therapy types ranging from small molecules, peptides, enzymes, oligonucleotides, gene therapy (viral vectors – e.g.. AAVs), and immunotherapies (antibody/vaccine immunotherapies). Complemented by our drug development service offering (such as target validation, biomarker identification, and validation, as well as PK/PD profiling), the InnoSer team works with you to accelerate your drug development at every stage.
InnoSer supports you in identifying new drugs or applications, characterizing their pharmacological properties, and conducting safety and efficacy testing with state-of-the-art readout capabilities and histopathological analysis.
Preclinical Neurology Disease Model Catalogue
In Vitro Neurology Assays
Screen your lead candidate compounds using InnoSer’s in vitro neurology assays to progress to preclinical in vivo studies with confidence
Spasticity (Spa) Mouse Model
Study novel interventions to improve physical performance in patients affected by muscular Spasticity using the Spa mouse model
Fragile X Syndrome – Fmr1 KO Mouse Model
InnoSer offers unique preclinical behavioural research studies using Fmr1 knock-out (KO) mouse model
Naturally Aged Mouse Model
Investigate relevant compounds to promote increased human longevity and healthy ageing thanks to our experience with InnoSer’s naturally aged mouse model
Alzheimer's Disease Mouse Models
InnoSer offers APP transgenic mice as well as transgenic Tau and Tau seeding models using recombinant and/or patient-derived seeds.
Multiple Sclerosis Mouse Models
Test novel compounds targeting Multiple Sclerosis with the support of our services in de- and re-myelinating multiple sclerosis mouse models
Infantile Epileptic Encephalopathy – Stxbp1 Mouse Model
Accelerate the availability of targeted therapies that improve the quality of lives of STXBP1-epileptic encephalopathy patients using the Stxbp1 mouse model
Parkinson's Disease Mouse Models
InnoSer offers MPTP mouse model, transgenic alpha-synuclein, or seeding alpha-synuclein mouse models using recombinant and/or patient-derived seeds.
Spinal Cord Injury (SCI) Mouse Model
Investigate your novel therapy’s potential in spinal cord regeneration using InnoSer’s clinically relevant spinal cord injury (SCI) mouse model
Charcot Marie Tooth Disease Type 1A C3-PMP22 Mouse Model
Mutations in the PMP22 gene cause several forms of neuropathies such as Charcot-Marie-Tooth Disease Type 1A
Amyotrophic Lateral Sclerosis (ALS) Mouse Models
Explore our advanced preclinical ALS mouse models, crucial for preclinical efficacy studies and understanding disease mechanisms
Duchenne Muscular Dystrophy (DMD) Mouse Model
Perform behavioural research studies to investigate your novel and innovative targeted Duchenne Muscular Dystrophy therapies using the DMD mouse model
Vanishing White Matter (eIF2B) Mouse Models
InnoSer offers unique services with an Eif2b4 / Eif2b5 mouse model of vanishing white matter (VWM)
Don’t See Your Model? We Can Help!
Our experts specialize in tailored solutions to meet your unique research needs. Let’s discuss how we can support your project.
Elevate Your Research With Additional Services
Readouts & Analyses
- Full suite of histopathology services
- Immunohistochemistry of brain and nerve tissues (IHC)
- Bioanalyses in various biological matrices
- Flow Cytometry
- ELISA, Ultra-Sensitive ELISA for CSF/plasma biomarkers
- Meso Scale Discovery (MSD)
- Immunoblotting
In Vivo Analyses
- Mouse breeding and genotyping
- Microbiome transplantation studies
- Compound administration
- Stereotaxic surgery
- EEG, EMG and ECG analyses
- Cannula implantation
- Tissue collection and analysis
The People Behind Your Research
Jolien Beekens, PhD, In Vitro Neurology Study Director
With in vitro screening methods available as a suited first step in your development process our team of experts have the experience to optimise your study design process.
Thomas Vogels, PhD, In Vivo Neurology Study Director
Leads an expert team of scientists with vast experience in our Neurology models to help you choose the right model and guide your optimal study design. We provide the solution to accelerating your drug development.
Your Neurology Research Starts Here.
Choose the Right Model for Your Research with Confidence
Stay Curious: More Articles to Explore
MDX Mouse Model Validation Data
This month we’re highlighting one of the most commonly used mouse models to study Duchenne Muscular Dystrophy (DMD) – the MDX mouse model B10.mdx), and explore how our advanced services can support your efficacy studies in DMD. The X-linked muscular dystrophy (MDX)...
InnoSer Announces Joint Initiative with Hasselt University/BIOMED to Support Preclinical Multiple Sclerosis Research
Researchers will benefit from InnoSer’s preclinical drug development expertise combined with Hasselt University’s foundational knowledge in Multiple Sclerosis (MS) to advance preclinical MS research. Diepenbeek, Belgium, October 16th, 2024 — InnoSer, a leading...
Introduction to InnoSer’s Preclinical Epilepsy Research CRO Platform
Preclinical epilepsy-related research with InnoSer Broadly speaking, epilepsy is a large spectrum of distinct epileptic syndromes that differ in their etiologies, mechanisms, pathophysiological processes, associated comorbidities, and response profile to available...
Phenotyping of a C3-PMP22 mouse model of CMT1A
Charcot-Marie Tooth (CMT) disease is a hereditary, demyelinating peripheral neuropathy, leading to progressive muscle atrophy, weakness and subsequent walking disabilities and sensory impairments. Charcot-Marie Tooth Type 1A (CMT1A) is the most common type of CMT,...
AAALAC Accreditation
InnoSer has earned the AAALAC accreditation, demonstrating our commitment to responsible animal care and use. AAALAC International is a nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. Our accreditation is valid for three years, incl. 2023. Read more about the AAALAC accreditation programme here.
Animal Welfare
The 3Rs impact everything from policy and regulatory change to the development and uptake of new technologies and approaches. This is why InnoSer has ongoing commitment and monitoring of these processes. The steps we practice maximize our ability to replace, reduce and refine animal involvement and facilitate our commitment to these principles when it comes to research and drug development.
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