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Home-Cage Behavior Discriminates Neurodegeneration Models from Healthy Aging Mice
Distinguishing pathological neurodegeneration from normal biological aging is a fundamental challenge in preclinical neuroscience. Presented at AD/PD 2023 in Gothenburg, this poster — developed in collaboration with Sylics and VU University Amsterdam — establishes a...
High-Fat Cholesterol and Fructose Diet Induces Cognitive Deficits in a Mouse Model of NAFLD
Epidemiological evidence suggests that western-style diet and the resulting non-alcoholic fatty liver disease (NAFLD) negatively impact cognitive performance, yet this relationship had not been formally investigated in a mouse model. Presented at the 6th Global NASH...
Full Phenotypic Characterization of an Adult-Onset ADPKD Mouse Model for Extended Disease Monitoring of Novel ADPKD Therapeutics
Autosomal dominant polycystic kidney disease (ADPKD) shows heterogeneous disease onset and progression in patients, demanding preclinical models that capture the full natural history of the condition. Presented at the 8th CKD Drug Development Summit in Boston (2026),...
Early Phenotypic Characterization of TDP-43 Q331K Mouse Model of ALS Reveals Elevated Plasma Neurofilament Light, Nerve Conduction Abnormalities and Behavioral Deficits
TDP-43 pathology underlies 97% of all ALS cases, making the TDP-43(Q331K) transgenic mouse a clinically relevant preclinical tool. Presented at SfN Neuroscience 2025 in San Diego, this poster provides longitudinal phenotypic characterization of female TDP-43(Q331K)...
![Characterizing Sex Differences in the Tau[P301S] Mouse Model of Tauopathies](https://www.innoserlaboratories.com/wp-content/uploads/2026/03/CHARACTERIZING-SEX-DIFFERENCES-IN-THE-TAUP301S-MOUSE-MODEL-OF-TAUOPATHIES--400x250.png)
Characterizing Sex Differences in the Tau[P301S] Mouse Model of Tauopathies
Sex differences in preclinical tauopathy models remain undercharacterized, yet they carry important implications for study design and translational validity. Presented at AD/PD 2026 in Copenhagen, this poster describes a longitudinal phenotyping study of male and...
Characterisation of In Vitro Neuronal and Microglial Disease Models to Support Drug Discovery Efforts for Neurodegenerative Diseases
Efficient in vitro screening platforms are essential for accelerating drug discovery in Alzheimer's and Parkinson's disease. Presented at AD/PD 2024 in Lisbon and updated for AD/PD 2025 in Vienna, this poster from our Belgium neurology team presents validated...
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