Previously, we have briefly introduced you to the Stxbp1 +/- mouse model of early infantile epileptic encephalopathies. Patients with a mutation in the STXBP1 gene (Syntaxin-binding protein 1, encoding the presynaptic protein Munc18-1) can receive a variety of...
Modelling neurodegenerative disease using in vitro assays Neurodegenerative drug development is held back due to the lack of appropriate models that help accelerate the pace at which novel therapeutic candidates move through the drug development pipeline. As such, in...
Delayed-type hypersensitivity (DTH) in vivo assay represents a relatively quick and useful approach for evaluating the efficacy of potential immunomodulatory or immunosuppressive compounds. By challenging the cell-mediated immune response, you obtain valuable...
At InnoSer, we offer several readouts to assess the disease progression and the efficacy of novel targeted polycystic kidney disease (PKD) compounds. However, we understand that it remains a significant challenge to access crucial readouts that are recognized by...
It is well-established that syngeneic tumour models represent a powerful tool to evaluate therapies that target the immune system. The key to understanding your immuno-modulatory compound’s efficacy is to work with well-characterised models, with known growth...
July is Fragile X Syndrome (FXS) Awareness month, a time dedicated to raising awareness about this rare genetic disorder, affecting thousands of individuals worldwide. We are deeply committed to accelerating the availability of targeted therapies to improve the lives...
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