Getting the Most out of Bioluminescent Imaging for Your Research

Getting the Most out of Bioluminescent Imaging for Your Research

The application of bioluminescence imaging (BLI) in preclinical research studies offers quantitative, sensitive, longitudinal real-time data and can be applied in:  Validation of cancer cell lines, helping to establish improved preclinical cancer mouse models. ...
The Application of Cystic Index in the ADPKD Mouse Model 

The Application of Cystic Index in the ADPKD Mouse Model 

The kidneys of autosomal dominant polycystic kidney disease (ADPKD) patients progressively enlarge due to the formation and expansion of fluid-filled cysts. However, currently there is no available therapy for ADPKD patients that targets the growth of cysts,...
eIF2B Modulators in Vanishing White Matter

eIF2B Modulators in Vanishing White Matter

Vanishing White Matter (VWM) disease is a rare and fatal leukodystrophy, caused by recessive mutations in the five genes encoding the protein complex eukaryotic translation initiation factor 2B (eIF2B). eIF2B plays a crucial role in initiating and regulating the...