Drug efficacy in vivo studies At InnoSer, we frequently carry out in vivo efficacy studies in a range of preclinical models (patient-derived xenografts, syngeneic models, cell-line derived xenografts) complemented with readouts such immune cell profiling and...
Introduction into the power of bioluminescence imaging Bioluminescence imaging (further referred to as BLI in this article) is an in vivo imaging technique that allows non-invasive longitudinal monitoring of in vivo processes, commonly applied in preclinical oncology...
For all novel therapy types in the immuno-oncology field such as immunotherapies, small molecule, biologics, ATMPs, gene therapeutics etc., rigorous preclinical research is the key to success in clinical trials. Learn more about how InnoSer’s expertise in the...
The application of bioluminescence imaging (BLI) in preclinical research studies offers quantitative, sensitive, longitudinal real-time data and can be applied in: Validation of cancer cell lines, helping to establish improved preclinical cancer mouse models. ...
Delayed-type hypersensitivity (DTH) in vivo assay represents a relatively quick and useful approach for evaluating the efficacy of potential immunomodulatory or immunosuppressive compounds. By challenging the cell-mediated immune response, you obtain valuable...
It is well-established that syngeneic tumour models represent a powerful tool to evaluate therapies that target the immune system. The key to understanding your immuno-modulatory compound’s efficacy is to work with well-characterised models, with known growth...
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