Relevant in vivo studies and in vitro immuno-oncology assays

Relevant in vivo studies and in vitro immuno-oncology assays

Drug efficacy in vivo studies  At InnoSer, we frequently carry out in vivo efficacy studies in a range of preclinical models (patient-derived xenografts, syngeneic models, cell-line derived xenografts) complemented with readouts such immune cell profiling and...
Assessment of Disease Progression in the ADPKD Mouse Model

Assessment of Disease Progression in the ADPKD Mouse Model

A significant challenge in the ADPKD research field is demonstrating efficacy of novel compounds in preclinical research models using clinically relevant endpoints. To date, total kidney volume (TKV) is the only FDA and EMA-approved imaging biomarker that is used as a...
Latest cardiovascular and metabolic research news

Latest cardiovascular and metabolic research news

InnoSer offers a selection of gold standard cardio-metabolic disease models in rodents, supporting custom studies to optimize the preclinical development of your drug candidates. Learn more about you can leverage InnoSer’s experience and expertise in the...
Assessment of Disease Progression in the ADPKD Mouse Model

PK/PD and Tolerability Testing in the ADPKD Mouse Model

The lead optimisation phase is a crucial process during which you investigate and select the most promising preclinical candidate(s) to progress to efficacy testing using animal models of human diseases. Pharmacokinetic (PK) and Pharmacodynamic (PD) profiling helps...