RENCA Mouse Mouse Model of Renal Cancer

RENCA Mouse Mouse Model of Renal Cancer

Approximately 400,000 people are diagnosed with kidney cancer annually. Kidney tumors are classified into different subtypes based on the cell of origin. Over 85% of malignant renal cell tumors are RCC, with the other 15% being nephroblastic, mesenchymal and...
Phenotyping of a C3-PMP22 mouse model of CMT1A 

Phenotyping of a C3-PMP22 mouse model of CMT1A 

Charcot-Marie Tooth (CMT) disease is a hereditary, demyelinating peripheral neuropathy, leading to progressive muscle atrophy, weakness and subsequent walking disabilities and sensory impairments. Charcot-Marie Tooth Type 1A (CMT1A) is the most common type of CMT,...
Glomerular filtration rate (GFR) in the ADPKD mouse model

Glomerular filtration rate (GFR) in the ADPKD mouse model

Preclinical studies aiming to assess kidney function traditionally include readouts such as serum creatinine and/or blood urea nitrogen (BUN). However, the use of readouts that are more clinically relevant such as glomerular filtration rate (GFR) is highly encouraged,...